Nelilma Correia Romeiro (UFRJ)
Professor at the Federal University of Rio de Janeiro, Macaé, RJ.
Lecture: Molecular modeling in the genomics era: opportunities and challenges.
Abstract: Advances in genomics have broadened the access to protein structures as therapeutic targets and interactions with other proteins or ligands. Dealing with such data opens opportunities to molecular modelling and rational drug design but also requires different tools in order to deepen the comprehension on molecular recognition mechanisms and challenges the predictive ability of such strategies. Chemogenomics applied to drug repurposing and target fishing will be given as examples of the application of modelling tools and usage of phenotypic data in drug discovery.