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Coordinator: Prof. Vinicius Farias Campos Academic Profile
UFPel geographical area of influence is abundant with water resources, an environment conducive to the development of several pathogenic microorganisms. One of the main diseases related to this type of environment is Leptospirosis. In this sense, the university has researched, in national and international partnerships, solutions based on reverse vaccinology for this disease maintaining an agreement with great international Universities such as University of Connecticut in the Health Center, with the project of research in spirochetes of medical importance.
In the same line, a project approved by the Royal Society for the identification of candidate antigens for vaccination and diagnosis based on the structural and reverse vaccinology and on the immunoprotein of Leptospira spp., in addition to a project for the development of vaccine adjuvants in partnership with the University of Lisbon.
In Canada, it maintains projects with the Vaccine and Infectious Disease Organization (VIDO) – International Vaccine Center of the University of Saskatchewan. Another important research front at UFPel has been the studies of diseases caused by Mycobacteria, such as tuberculosis.
Among these studies, one can highlight the work carried out with the Instituto Pasteur de Montevideo for the Transcriptome of M. tuberculosis, the work “Genotyping of M. tuberculosis at the borders”, carried out jointly with the Honorary Commission for tuberculosis control and prevalent diseases of the Uruguay and the project “BioBricks: synthetic biology technology for rationale and efficient design of live attenuated recombinant BCG vaccines”, conducted in partnership with the University of Surrey.