Seminário Prof. Claudio Santi

Resumo do Seminário:
During the current pandemic diffusion of SARS-Cov2 and the several cases of COVID-19 that killed thousands of people all around the world forcing millions of people to sty locked at home, having smart working and cancelling almost completely social relationships a number of no-news non-correct news  or completely false news were spread by social, media and also some too much  speculative scientific publications. We try to clarify some of these news making the point on which is the state of art in the studies of selenium and sulphur in  the battle against the new coronavirus. In particular  it will be focused the attention on the pro-oxidant activities of some selenium derivatives that  our network some proposed as the most promising approach in the use of organoselenium derivatives in medicinal chemistry, and that seems to have a rationale also in the development of new drugs against SARS-Cov2.

* Este webinar é uma atividade do projeto “Moléculas bioativas contendo selênio – Síntese, caracterização e aplicações”, da proposta institucional CAPES-PrInt/UFPel 2019.  

SHORT CV – prof Claudio Santi (para a página do PPGQ)

 Prof. Claudio Santi obtained his PhD in Chemical Sciences in 1996 under the supervision of Prof. Marcello Tiecco and in 1998, he spent a period as postdoc in the group of Prof. Thomas Wirth at Basel University. Since 2013 he is associated professor of Organic Chemistry and leads the group of Catalysis Synthesis and Organic Green Chemistry. In the framework of the national scientific habilitation (ASN) process he was acknowledged as Full Professor (since 11/12/2013) for Organic Chemistry. He has been invited as visiting professor in Jan Dlugosz University of Czestochowa-PL (2013) Universidade Federal de Pelotas – Brazil (2014), Universidade Federal de Minas Gerais (2020) and, under the Erasmus scheme he teach  organic chemistry in Jagiellonian University Krakow (1997) Cardiff University (1999), Univesidad Complutense de Madrid (2016).

In 2012 he co-founded and still leads the international research Network on Selenium Sulfur Redox and Catalysis (SeSRedCat). He is author of 155 peer reviewed articles, 6 book chapters, two books and several special issues. (H-index 37). He acts in a number of editorial and scientific boards including Current Chemical Biology (Bentham) es Editor in Chief,  Molecules (MDPI) International Journal of Molecular Sciences (MDPI) as member of the EB. He received many honors and awards: top 10% of highly cited authors of RSC (2016); Fellow of the Royal Society of Chemistry (2017), listed in the top Italian Scientists (Via-Academy) since 2018; appointed as honorary professors at Jan Dlugosz University of Czestochowa-PL (2018).

Internationally recognized expert in organoselenium chemistry, he pioneered the studies on the use of optically pure diselenides in asymmetric synthesis. He was the first to envision the possibility to use selenium containing catalyst in Green Chemistry and he developed the first class of bench stable nucleophilic zinc selenates like the PhSeZnCl nowadays commercially available under the name of “Santi’s Reagent”. He recently extended his scientific interest to the biological activity of some organoselenium derivatives as well as to the investigation of the catalytic mechanism of naturally occurring selenoproteins.

He advised and coadvised 12 PhD students and more than 100 Master students in chemistry and medicinal chemistry.