{"id":436,"date":"2022-01-22T10:53:55","date_gmt":"2022-01-22T13:53:55","guid":{"rendered":"https:\/\/wp.ufpel.edu.br\/bionano\/?page_id=436"},"modified":"2022-01-22T10:53:55","modified_gmt":"2022-01-22T13:53:55","slug":"biological-potential-of-hydroalcoholic-extracts-of-physalis-pubescens-l","status":"publish","type":"page","link":"https:\/\/wp.ufpel.edu.br\/bionano\/producao-cientifica\/2021-2\/biological-potential-of-hydroalcoholic-extracts-of-physalis-pubescens-l\/","title":{"rendered":"Biological potential of hydroalcoholic extracts of Physalis pubescens L"},"content":{"rendered":"<h3><em><strong><span class=\"content\"><span class=\"text given-name\">Tailise Beatriz Roll<\/span><span class=\"text surname\">Zimmer, <\/span><\/span><span class=\"content\"><span class=\"text given-name\">Deborah Murowaniecki <\/span><span class=\"text surname\">Otero, <\/span><\/span><span class=\"content\"><span class=\"text given-name\">Nathalia Stark <\/span><span class=\"text surname\">Pedra, <\/span><\/span><span class=\"content\"><span class=\"text given-name\">Nat\u00e1lia Pontes <\/span><span class=\"text surname\">Bona, <\/span><\/span><span class=\"content\"><span class=\"text given-name\">Leticia <\/span><span class=\"text surname\">Zarnott, <\/span><\/span><span class=\"content\"><span class=\"text given-name\">Roselia Maria <\/span><span class=\"text surname\">Spanevello, <\/span><\/span><span class=\"content\"><span class=\"text given-name\">Eliezer Avila <\/span><span class=\"text surname\">Gandra, <\/span><\/span><span class=\"content\"><span class=\"text given-name\">Rui Carlos <\/span><span class=\"text surname\">Zambiazi<\/span><\/span><\/strong><\/em><\/h3>\n<h3 class=\"section-title u-h3 u-margin-l-top u-margin-xs-bottom\"><strong>Abstract<\/strong><\/h3>\n<div id=\"abssec0010\">\n<h3 id=\"abspara0010\" style=\"text-align: justify\">The antioxidant, antibacterial, and antitumor effects of hydroalcoholic extracts of the pulp and seeds of\u00a0<em>Physalis pubescens<\/em>\u00a0L. were explored. The components of the extracts were identified and quantified by high-performance liquid chromatography (HPLC). The antioxidant activity was determined by 2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and ferric reducing antioxidant power (FRAP) analyses. The antibacterial activity against\u00a0<em>Staphylococcus aureus<\/em>,\u00a0<em>Listeria monocytogenes<\/em>, and\u00a0<em>Escherichia coli<\/em>\u00a0was evaluated by using a diffusion disc. Cytotoxicological assays that were performed using glioblastoma cell lines from C6 and GL26 mice and murine melanoma cell lines (B16F10), in addition to primary astrocyte culture. Fourteen phenolic compounds were identified, where epicatechin was the dominant. High antioxidant activity of both the pulp (2210.46\u00a0\u03bcM of Trolox\/g) and seeds (2807.74\u00a0\u03bcM trolox\/g) was observed by the DPPH method. The pulp and seed extracts showed moderately active inhibition halos in the presence of Gram-positive bacteria. Both extracts were able to reduce the percentage cell viability.<\/h3>\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.bcab.2020.101895\">https:\/\/doi.org\/10.1016\/j.bcab.2020.101895<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Tailise Beatriz RollZimmer, Deborah Murowaniecki Otero, Nathalia Stark Pedra, Nat\u00e1lia Pontes Bona, Leticia Zarnott, Roselia Maria Spanevello, Eliezer Avila Gandra, Rui Carlos Zambiazi Abstract The antioxidant, antibacterial, and antitumor effects of hydroalcoholic extracts of the pulp and seeds of\u00a0Physalis pubescens\u00a0L. were explored. The components of the extracts were identified and quantified by high-performance liquid chromatography&#8230; <\/p>\n<div class=\"link-more\"><a href=\"https:\/\/wp.ufpel.edu.br\/bionano\/producao-cientifica\/2021-2\/biological-potential-of-hydroalcoholic-extracts-of-physalis-pubescens-l\/\">Leia mais<\/a><\/div>\n","protected":false},"author":1158,"featured_media":0,"parent":373,"menu_order":18,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-436","page","type-page","status-publish","hentry"],"publishpress_future_action":{"enabled":false,"date":"2026-04-24 00:48:27","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/pages\/436","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/users\/1158"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/comments?post=436"}],"version-history":[{"count":1,"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/pages\/436\/revisions"}],"predecessor-version":[{"id":438,"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/pages\/436\/revisions\/438"}],"up":[{"embeddable":true,"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/pages\/373"}],"wp:attachment":[{"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/media?parent=436"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}