{"id":421,"date":"2022-01-22T10:28:47","date_gmt":"2022-01-22T13:28:47","guid":{"rendered":"https:\/\/wp.ufpel.edu.br\/bionano\/?page_id=421"},"modified":"2022-01-22T10:28:47","modified_gmt":"2022-01-22T13:28:47","slug":"risk-assessment-of-in-vitro-cytotoxicity-antioxidant-and-antimicrobial-activities-of-mentha-piperita-l-essential-oil","status":"publish","type":"page","link":"https:\/\/wp.ufpel.edu.br\/bionano\/producao-cientifica\/2021-2\/risk-assessment-of-in-vitro-cytotoxicity-antioxidant-and-antimicrobial-activities-of-mentha-piperita-l-essential-oil\/","title":{"rendered":"Risk assessment of in vitro cytotoxicity, antioxidant and antimicrobial activities of Mentha piperita L. essential oil"},"content":{"rendered":"<h3><em><strong><span style=\"color: #333333\">W. M. F. Silva, N. P. Bona, N. S. Pedra, K. F. Da Cunha, A. M. Fiorentini, <\/span><span style=\"color: #333333\">F. M. Stefanello<\/span><span class=\"NLM_contrib-group\" style=\"color: #333333\"><span class=\"contribDegrees \">, <\/span><\/span><span style=\"color: #333333\">E. R. Zavareze, <\/span><span style=\"color: #333333\">A. R. G. Dias<\/span><\/strong><\/em><\/h3>\n<div class=\"sectionHeading\"><strong>ABSTRACT<\/strong><\/div>\n<div class=\"abstractSection abstractInFull\">\n<h3 style=\"text-align: justify\">The objective of this study was to determine the chemical composition as well as antioxidant, antibacterial, and cytotoxic properties of the essential oil of\u00a0<i>Mentha piperita<\/i>\u00a0L. (peppermint). Fifteen chemical constituents were identified in the essential oil, for a total of 99.99% of the compounds. The essential oil exhibited antimicrobial activity against two Gram-positive bacteria\u00a0<i>Staphylococcus aureus<\/i>\u00a0and\u00a0<i>Listeria monocytogenes<\/i>. The minimum inhibitory concentration (MIC) of essential oil of\u00a0<i>Mentha piperita<\/i>\u00a0L. for\u00a0<i>Staphylococcus aureus<\/i>\u00a0and\u00a0<i>Listeria monocytogenes<\/i>\u00a0was 1.84\u00a0\u03bcg\/ml, whereas the minimum bactericidal concentration (MBC) values were 3.7 and 7.43\u00a0\u03bcg\/ml, respectively. The oil displayed potent antioxidant activity inhibiting up to approximately73% of 2,2\u02b9-azinothiobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals. In the cytotoxicity assay, the highest essential oil concentration (100\u00a0\u03bcg\/ml) resulted in viability of approximately 90% human epidermal keratinocyte (HaCaT) cells. With respect to antitumor activity in C6 rat glioma cells, there was significant reduction in cell viability: 56\u201374% in 24\u00a0hr, and 71\u201377% in 48\u00a0hr. Data suggest that in presence of the essential oil of\u00a0<i>Mentha piperita<\/i>\u00a0L. antioxidant, antibacterial, antitumor and non-cytotoxic properties were noted.<\/h3>\n<p><a href=\"https:\/\/doi.org\/10.1080\/15287394.2021.1999875\">https:\/\/doi.org\/10.1080\/15287394.2021.1999875<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>W. M. F. Silva, N. P. Bona, N. S. Pedra, K. F. Da Cunha, A. M. Fiorentini, F. M. Stefanello, E. R. Zavareze, A. R. G. Dias ABSTRACT The objective of this study was to determine the chemical composition as well as antioxidant, antibacterial, and cytotoxic properties of the essential oil of\u00a0Mentha piperita\u00a0L. (peppermint). Fifteen&#8230; <\/p>\n<div class=\"link-more\"><a href=\"https:\/\/wp.ufpel.edu.br\/bionano\/producao-cientifica\/2021-2\/risk-assessment-of-in-vitro-cytotoxicity-antioxidant-and-antimicrobial-activities-of-mentha-piperita-l-essential-oil\/\">Leia mais<\/a><\/div>\n","protected":false},"author":1158,"featured_media":0,"parent":373,"menu_order":13,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-421","page","type-page","status-publish","hentry"],"publishpress_future_action":{"enabled":false,"date":"2026-04-23 01:52:00","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/pages\/421","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/users\/1158"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/comments?post=421"}],"version-history":[{"count":1,"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/pages\/421\/revisions"}],"predecessor-version":[{"id":423,"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/pages\/421\/revisions\/423"}],"up":[{"embeddable":true,"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/pages\/373"}],"wp:attachment":[{"href":"https:\/\/wp.ufpel.edu.br\/bionano\/wp-json\/wp\/v2\/media?parent=421"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}